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 Reproductive & Neuro-Endocrinology

PT-141

PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and is commonly utilized in biochemical and molecular research involving melanocortin receptor interactions. In controlled laboratory settings, PT-141 is studied for its interaction with melanocortin receptor subtypes and its role in intracellular signaling pathway analysis under defined in vitro conditions. This material is supplied in lyophilized powder form and is intended strictly for in vitro research and analytical applications.

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Product Usage: Not for Human or Veterinary UsePure Health Peptides products are supplied to qualified research professionals and institutional users for in vitro laboratory research only. KYC verification is required prior to order fulfillment, and we reserve the right to refuse orders that do not meet buyer qualification criteria. These products are not drugs, foods, cosmetics, diagnostic products, or dietary supplements, have not been evaluated by the FDA, and are not intended for human or animal use. Any such use is prohibited and may violate federal, state, or local law. By purchasing, the buyer represents and warrants that the product will be used solely for in vitro research. The buyer agrees to indemnify, defend, and hold harmless Pure Health Peptides, its officers, employees, and agents from and against any and all claims, damages, losses, liabilities, costs, and expenses (including reasonable attorneys fees) arising out of or relating to the buyer’s use, handling, storage, or disposition of the product in any manner inconsistent with its research-use-only designation or applicable law.

Description

Product Name:

PT-141

Chemical Information:
  • Molecular Formula: C50H68N14O10
  • Molecular Weight: 1025.2 g/mol
  • Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Molecular Structure:




Molecular Structure

Product Description:

PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and is commonly utilized in biochemical and molecular research involving melanocortin receptor interactions. In controlled laboratory settings, PT-141 is studied for its interaction with melanocortin receptor subtypes and its role in intracellular signaling pathway analysis under defined in vitro conditions. This material is supplied in lyophilized powder form and is intended strictly for in vitro research and analytical applications.

Research Applications:

PT-141 is utilized in controlled research environments to support investigation of:

  • Melanocortin receptor binding and signaling pathway analysis
  • Peptide–receptor interaction dynamics in melanocortin system models
  • Intracellular signaling cascade evaluation associated with peptide ligands
  • Structure-function relationships of cyclic peptide analogs
  • Stability, degradation, and analytical profiling in assay-based systems

All research applications are conducted in non-human, non-clinical experimental settings.

Storage and Handling:
  • Store lyophilized material at −20°C (−4°F)
  • After reconstitution, store at 2–8°C (36–46°F) and use promptly
  • Avoid repeated freeze-thaw cycles
  • Maintain aseptic laboratory handling procedures
Product Specifications:
  • Purity: ≥99% (HPLC Certified)
  • Appearance: Lyophilized white powder
  • Solubility: Soluble in suitable laboratory agents
Compliance Notice:

PT-141 is FOR RESEARCH USE ONLY as an analytical reference material. PT-141 is the active ingredient of an FDA-approved pharmaceutical product (Vyleesi®). This research material is not the approved drug product, is not intended for human or veterinary use, and has not been independently evaluated by the FDA as a research compound. Buyers are solely responsible for determining the legality of this compound in their jurisdiction, including compliance with the Federal Analog Act (21 U.S.C. § 813) and any applicable state analog statutes. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Certificate of Analysis

Certificate of Analysis

At Pure Health Peptides, transparency is key. Every batch is third-party tested in the USA, with Certificates of Analysis (COAs) readily available for verification, giving researchers confidence in their work.

View Certifications

Frequently Asked Questions

What is PT-141?
PT-141 is a synthetic cyclic heptapeptide and a melanocortin-receptor agonist, corresponding to bremelanotide (an analog of alpha-melanocyte-stimulating hormone). It has molecular formula C50H68N14O10 and a molecular weight of 1025.2 g/mol, with sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Pure Health Peptides supplies it as a lyophilized powder strictly for in vitro laboratory research.
What is PT-141 studied for in research?
In controlled laboratory settings, PT-141 is studied as an agonist of the melanocortin receptors (including MC3R and MC4R). Research literature examines melanocortin-pathway signaling using this compound. These are non-clinical research applications; the material is not supplied for any therapeutic purpose.
Is PT-141 the same as the approved drug Vyleesi?
PT-141 corresponds to bremelanotide, which is the active ingredient in an FDA-approved pharmaceutical product (Vyleesi). However, this research material is not that approved drug product - it is unapproved research-grade material supplied strictly for in vitro laboratory research, and it falls under the Federal Analog Act framework. It is not a substitute for, or equivalent to, any approved medication.
What is PT-141's chemical identity and classification?
PT-141 is a cyclic (lactam-bridged) heptapeptide of the melanocortin-agonist class, molecular formula C50H68N14O10, molecular weight 1025.2 g/mol, sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It is a defined synthetic peptide characterized as a research reference material.
What are PT-141's specifications, and what size does it come in?
PT-141 has the molecular formula C50H68N14O10 and a molecular weight of 1025.2 g/mol (refer to the lot-specific Certificate of Analysis for the exact value). It is supplied as a lyophilized white powder in a 10 mg vial at greater than or equal to 99% purity (HPLC). Store in a cool, dry place away from light and moisture.
Where can I buy PT-141, and is it third-party tested?
PT-141 is available from Pure Health Peptides as research-grade material in a 10 mg vial at greater than or equal to 99% HPLC-verified purity. Every production lot is third-party tested in the US, with a lot-specific Certificate of Analysis available for verification.
Is PT-141 intended for human or clinical use?
No. PT-141 is for research use only and is not intended for human or veterinary use. It has not been evaluated by the FDA and is not a drug, food, cosmetic, or dietary supplement. It is supplied only to qualified research professionals for in vitro laboratory research, and KYC verification is required prior to fulfillment. Any use outside of controlled in vitro research is strictly prohibited.