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Cellular Growth & Signaling

PEG-MGF

PEG-MGF is a pegylated synthetic peptide provided exclusively for in vitro laboratory research in controlled experimental settings. This material is intended for investigation of molecular pathways, peptide modification effects, and cellular interaction mechanisms by qualified research professionals. It is supplied in lyophilized powder form for analytical and reference purposes only.

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Product Usage: Not for Human or Veterinary UsePure Health Peptides products are supplied to qualified research professionals and institutional users for in vitro laboratory research only. KYC verification is required prior to order fulfillment, and we reserve the right to refuse orders that do not meet buyer qualification criteria. These products are not drugs, foods, cosmetics, diagnostic products, or dietary supplements, have not been evaluated by the FDA, and are not intended for human or animal use. Any such use is prohibited and may violate federal, state, or local law. By purchasing, the buyer represents and warrants that the product will be used solely for in vitro research. The buyer agrees to indemnify, defend, and hold harmless Pure Health Peptides, its officers, employees, and agents from and against any and all claims, damages, losses, liabilities, costs, and expenses (including reasonable attorneys fees) arising out of or relating to the buyer’s use, handling, storage, or disposition of the product in any manner inconsistent with its research-use-only designation or applicable law.

Description

Product Name:

PEG-MGF (Pegylated Mechano Growth Factor)

Chemical Information:
    • Molecular Formula: Not represented by a single fixed molecular formula due to the polydisperse nature of the PEG component
    • Molecular Weight: Nominal molecular weight varies depending on the PEG conjugate
    • Sequence: PEG-YQPPSTNKNTKSQRRKGSTFEERK
    • Note: PEGylated compounds differ from conventional peptides because the polyethylene glycol component is inherently polydisperse. Consequently, certain physicochemical properties (such as molecular formula and exact molecular weight) are represented by batch-specific analytical values rather than a single universal constant.
    • Molecular Structure: (Structure not shown due to variability in PEG modification by manufacturer)
    Product Description:

    PEG-MGF is a pegylated synthetic peptide provided exclusively for in vitro laboratory research in controlled experimental settings. This material is intended for investigation of molecular pathways, peptide modification effects, and cellular interaction mechanisms by qualified research professionals. It is supplied in lyophilized powder form for analytical and reference purposes only.

    Research Applications:

    PEG-MGF is utilized in controlled research environments to support investigation of:

    • Peptide–receptor interaction dynamics and signaling pathway analysis
    • Structure-function relationships of modified peptide analogs
    • Evaluation of pegylation effects on peptide stability, degradation, and interaction profiles
    • Intracellular signaling cascade analysis in peptide-based research models
    • Analytical characterization in assay-based experimental systems

    All research applications are conducted in non-human, non-clinical experimental settings.

    Storage and Handling:
    • Store lyophilized material at −20°C (−4°F)
    • After reconstitution, store at 2–8°C (36–46°F) and use promptly
    • Avoid repeated freeze-thaw cycles
    • Maintain aseptic techniques during laboratory handling
    Product Specifications:
    • Purity: ≥99% (HPLC Certified)
    • Appearance: Lyophilized white powder
    • Solubility: Soluble in suitable laboratory agents
    Compliance Notice:

    PEG-MGF is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Certificate of Analysis

Certificate of Analysis

At Pure Health Peptides, transparency is key. Every batch is third-party tested in the USA, with Certificates of Analysis (COAs) readily available for verification, giving researchers confidence in their work.

View Certifications

Frequently Asked Questions

What is PEG-MGF?
PEG-MGF is a PEGylated synthetic peptide - the C-terminal fragment of the E-domain of the IGF-1Ec splice variant (MGF, sequence PEG-YQPPSTNKNTKSQRRKGSTFEERK) with a polyethylene glycol (PEG) chain covalently attached. Because the PEG component is polydisperse, PEG-MGF is not represented by a single fixed molecular formula, and its nominal molecular weight varies depending on the PEG conjugate. Pure Health Peptides supplies it as a lyophilized powder strictly for in vitro laboratory research.
What does PEGylation mean, and how does PEG-MGF differ from MGF?
PEGylation is the covalent attachment of a polyethylene glycol chain to a peptide. Research literature reports that PEGylation increases a molecule's effective size and shields it from enzymatic degradation, extending its stability in study models relative to the unmodified peptide. PEG-MGF and MGF are supplied as separate, individually characterized research compounds.
Why doesn't PEG-MGF have one fixed molecular formula?
Unlike conventional peptides, PEG-MGF consists of an MGF peptide chemically conjugated to polyethylene glycol (PEG). The PEG component is inherently polydisperse, meaning it contains a distribution of polymer chain lengths rather than a single uniform structure. As a result, PEG-MGF does not possess one universally fixed molecular formula or exact molecular weight. Analytical testing is performed on the specific batch being evaluated, and representative values reported on a Certificate of Analysis apply to that tested material. This behavior is characteristic of PEGylated compounds and should not be interpreted as an indication of inconsistent manufacturing or reduced analytical quality.
What is PEG-MGF studied for in research?
In controlled laboratory settings, PEG-MGF is studied as a PEGylated form of the IGF-1Ec E-domain fragment. Research literature reports that this E-peptide is examined in models of muscle satellite (stem) cell activation, and that PEGylation is used to study the effect of peptide modification on stability. These are research findings; all applications are non-clinical.
What size does PEG-MGF come in, and is it third-party tested?
PEG-MGF is supplied as a lyophilized white powder in 2 mg and 5 mg vials. Because the PEG component is not a single fixed structure, purity is reported per lot on the Certificate of Analysis rather than as a fixed figure. Every production lot is third-party tested in the US, with a lot-specific Certificate of Analysis available for verification. Store in a cool, dry place away from light and moisture, and consult the Safety Data Sheet before handling.
Is PEG-MGF intended for human or clinical use?
No. PEG-MGF is for research use only and is not intended for human or veterinary use. It has not been evaluated by the FDA and is not a drug, food, cosmetic, or dietary supplement. It is supplied only to qualified research professionals for in vitro laboratory research, and KYC verification is required prior to fulfillment. Any use outside of controlled in vitro research is strictly prohibited.