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Metabolic Research, Mitochondrial & Cellular Energy

AICAR

AICAR is a synthetic nucleotide analog commonly used as a reference compound in laboratory research involving cellular and biochemical assay systems. It is not a peptide and is produced via chemical synthesis rather than amino acid assembly.

Supplied as a solid research material, AICAR is intended exclusively for controlled in-vitro laboratory research conducted by qualified professionals.

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Product Usage: Not for Human or Veterinary UsePure Health Peptides products are supplied to qualified research professionals and institutional users for in vitro laboratory research only. KYC verification is required prior to order fulfillment, and we reserve the right to refuse orders that do not meet buyer qualification criteria. These products are not drugs, foods, cosmetics, diagnostic products, or dietary supplements, have not been evaluated by the FDA, and are not intended for human or animal use. Any such use is prohibited and may violate federal, state, or local law. By purchasing, the buyer represents and warrants that the product will be used solely for in vitro research. The buyer agrees to indemnify, defend, and hold harmless Pure Health Peptides, its officers, employees, and agents from and against any and all claims, damages, losses, liabilities, costs, and expenses (including reasonable attorneys fees) arising out of or relating to the buyer’s use, handling, storage, or disposition of the product in any manner inconsistent with its research-use-only designation or applicable law.

Description

Product Name:

AICAR

Chemical Information:
  • Chemical Name: 5-Aminoimidazole-4-carboxamide ribonucleotide
  • Molecular Formula: C₉H₁₄N₄O₅
  • Molecular Weight: ~258.23 g/mol
  • Compound Class: Nucleotide analog (non-peptide)
Molecular Structure:



Molecular Structure

Product Description:

AICAR is a synthetic nucleotide analog commonly used as a reference compound in laboratory research involving cellular and biochemical assay systems. It is not a peptide and is produced via chemical synthesis rather than amino acid assembly.

Supplied as a solid research material, AICAR is intended exclusively for controlled in-vitro laboratory research conducted by qualified professionals.

Research Applications:
  • In-vitro studies involving nucleotide analog behavior in biochemical assay systems
  • Analytical method development for small-molecule and nucleotide-based compounds
  • Laboratory evaluation of compound stability and chemical interactions under controlled conditions
  • Comparative analysis of nucleotide analogs in non-clinical research environments
Storage and Handling:
  • Store in a cool, dry environment away from light
  • Keep container tightly sealed when not in use
  • Handle using appropriate laboratory safety and aseptic techniques
Product Specifications:
  • Purity: ≥99% (HPLC Certified)
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in common laboratory buffers
Compliance Notice:

AICAR is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Certificate of Analysis

Certificate of Analysis

At Pure Health Peptides, transparency is key. Every batch is third-party tested in the USA, with Certificates of Analysis (COAs) readily available for verification, giving researchers confidence in their work.

View Certifications

Frequently Asked Questions

What is AICAR?
AICAR (5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, also called acadesine) is a synthetic nucleoside analog with CAS number 2627-69-2, molecular formula C9H14N4O5, and a molecular weight of approximately 258.23 g/mol. Pure Health Peptides supplies it as a solid research material strictly for in vitro laboratory research.
Is AICAR a peptide?
No. AICAR is not a peptide - it is a nucleoside analog, a single defined small molecule rather than a chain of amino acids. Once inside cells it is phosphorylated to ZMP, the nucleotide that acts as the AMP mimetic.
What is AICAR studied for in research?
In controlled laboratory settings, AICAR is studied as an activator of AMP-activated protein kinase (AMPK). Research literature reports that, once taken up by cells and phosphorylated to the nucleotide ZMP, it mimics AMP and activates the AMPK pathway in study models. Note: AICAR appears on the World Anti-Doping Agency prohibited list. These are research findings; all applications are non-clinical.
What are AICAR's chemical specifications, and what size does it come in?
AICAR has CAS number 2627-69-2, the molecular formula C9H14N4O5, and a molecular weight of approximately 258.23 g/mol (refer to the lot-specific Certificate of Analysis for the exact value). It is supplied as a white to off-white crystalline powder in a 50 mg vial. Store in a cool, dry place away from light and moisture, and consult the Safety Data Sheet before handling.
Where can I buy AICAR, and is it third-party tested?
AICAR is available from Pure Health Peptides as research-grade material in a 50 mg vial. Every production lot is third-party tested in the US, with a lot-specific Certificate of Analysis available for verification.
Is AICAR intended for human or clinical use?
No. AICAR is for research use only and is not intended for human or veterinary use. It has not been evaluated by the FDA and is not a drug, food, cosmetic, or dietary supplement. It is supplied only to qualified research professionals for in vitro laboratory research, and KYC verification is required prior to fulfillment. Any use outside of controlled in vitro research is strictly prohibited.